Marsha Rosner (University of Chicago)

Signaling Pathways and Cancer: How can we suppress Metastasis?

Cancer is one of the leading causes of death in the world today. In most cases, the dissemination of tumor cells throughout the body in a process termed "metastasis" is actually what causes lethality. What do we know about the genes involved in this process and how can we control them? Studying the role of natural metastasis suppressor genes may give us a clue.

Marsha R. Rosner, Ph.D., is the Charles B. Huggins Professor and Chair of the Ben May Department for Cancer Research. She is also Director of the Cornelius Crane Laboratory for Eczema Research, and Deputy Director of the University of Chicago Cancer Research Center. She is the founder and past Chair of the Committee on Cancer Biology (CCB) at the University of Chicago. A graduate program that confers a Ph.D. degree in the field of Cancer Biology, the CCB has become one of the most successful graduate programs within the Division of Biological Sciences at the University of Chicago.

Dr. Rosner received her bachelor's degree in biochemistry from Harvard University, and she received her Ph.D. degree in biochemistry from the Massachusetts Institute of Technology, where she worked with Professor Gobind Khorana, who won the Nobel Prize for his work in elucidating the genetic code. Dr. Rosner then stayed at MIT to pursue postdoctoral work as a fellow of the American Cancer Society in the laboratory of Dr. Phillips Robbins. In 1982, she assumed her first faculty position as an Assistant Professor in the Dept. of Applied Biological Sciences at MIT. After promotion to Associate Professor at MIT, Dr. Rosner came to the University of Chicago in 1987.

Dr. Rosner is an internationally recognized authority in the field of signal transduction and has had a longstanding interest in elucidating the mechanisms by which growth factors promote the growth, differentiation or death of cells. The author or co-author of over 100 scientific publications, Dr. Rosner has served as a reviewer for a number of journals and is or has been a member of the Editorial Boards of Molecular Endocrinology, Gene Therapy and Molecular Biology, and the Journal of Biological Chemistry. Dr. Rosner has been a visiting Professor at the University of Palermo, and, in 1999, was elected a fellow of the Institute of Medicine of Chicago. Dr. Rosner was a member of the Scientific Advisory Board of the Children's Memorial Institute for Research at Northwestern University, and serves on the Board of Trustees of the Illinois Math and Science Academy. She is also a member of several professional societies including the AACR, the ASBC, the ASCB, and the Endocrine Society. Within the University of Chicago, Dr. Rosner has had numerous responsibilities including serving as a member of the University of Chicago on Council Research, the Dean's Advisory Committee, the Committee on Academic Fraud and as Chair of the Institutional Biosafety Committee. Nationally, she has been a member of scientific review panels for the American Cancer Society, the Veteran's Administration, and the National Institutes of Health where she also served as Chair of the Biochemistry study section. In 2001, she received the Quantrell award for excellence in undergraduate teaching at the University of Chicago.

Back to Symposium Agenda