Holly Goodson (University of Notre Dame)

Molecular Engines and Nano-Train-Tracks

Watch the talk (running time 45:18)

The cytoskeleton is a dynamic network of protein filaments, molecular motors, and accessory proteins that gives cells the ability to move, change shape, and organize themselves. There is now a great deal of interest in engineering "nanomachines" and in assembling them into larger complexes with varied functions. However, making and utilizing such nanomchines has proven to be harder than expected. The cytoskeleton is a beautiful example of an already-existing network of self-assembling biological nanomachines. If we can understand these biological nanomachines, perhaps we can harness them directly or use biology's solutions as a foundation for the next generation of human-designed nanotechnology.

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