How Do We Inherit Our Biological Characteristics

How Do We Inherit Tourette Syndrome?

Shelly Peretz
Science Department Chairperson
Thornridge High School

Office Phone: 708-225-4585

Photograph linked from Swedish Tourette Syndrome Association


Mike and Carrie Riley had always attributed to simple mischievousness the fact that four of their six children were considered troublemakers in school. Greg and Ken had the annoying habit of often repeating what was said to them, and both boys had been punished for suddenly yelling out obscenities in school. Alicia and Kate didn't yell, but they just could not sit still in school, always fidgeting, jerking their heads, blinking, and grimacing. So far, Joe and Cindy had no such mannerisms. Since their father Mike and his mother Rita also made these movements, everyone thought that the children had just picked up their father and grandmother's behavioral quirks from watching them.

Mike's niece and nephew, Edie and Steve, children of his sister Suzanne and her husband Adam, are generally healthy, but have peculiar habits. Edie takes about twenty showers a day and washers her hands dozens of times a day. Steve has dyslexia and also has great difficulty solving mathematical problems, such as balancing the checkbook and comparative shopping at the supermarket. Their third child Jenny is only two years old, and, so far, her behavior is normal.

Carrie's sister Vicki is in medical school. When she learns about Tourette syndrome, she immediately thinks of her troublesome nieces and nephews.

Your assignment for the next three weeks will be to investigate this disease and prepare a "story book" about the disease. The genetics counseling community ascribes to a belief in non-directive counseling. That is, they feel that it is their duty to provide all of the information that is available and desired by a family so that they can make the decisions that are appropriate to them based on their own cultural, moral, religious, etc. beliefs.

Your investigation should include medical information important for people with this disease so that they can live a healthy and prolonged life. This might include:

Each image must have a caption. The presentation will be given using ClarisWorks® or Microsoft PowerPoint® presentation software. It should be written such that someone else could view the presentation and understand the key points without an accompanying verbal explanation.

You may not violate copyright laws. Any images or other resources retrieved from the internet and used in your presentation must be accompanied by a reference telling where it was obtained.

Technology Support

Netscape Basics
Here you can find a wealth of helpful information about your Netscape software and how to overcome any problems you might encounter with it.
Finding Information
Finding what you want on the Internet can be like looking for a needle in a haystack. Online search tools help you track down whatever it is you're looking for.

Helpful Exercises

The following exercises were designed to help you understand human genetic diseases, including the medical facts, diagnosis, probable course of the disorder, and the available management. While these exercises are, of course, optional, you are strongly encouraged to complete them:

Guidelines for Reporting and Writing About People with Disabilities
The University of Kansas and other national associations have endorsed a a set of clear guidelines to help you make better choices in terms of language and portrayal. The "Guidelines" explain preferred terminology and offer suggestions for appropriate ways to describe people with disabilities.
Understanding Gene Testing
This represents an effort by the National Cancer Institute and the National Center for Human Genome Research to provide basic information about gene testing and key genetic concepts. This booklet also provides answers to a number of frequently asked questions about the science, potential benefits, and potential risks of gene testing.
Genetic Counseling: Coping With the Human Impact of Genetic Disease
Genetic Consultation/Counseling: The Process
Describes what they do and how they do it.
Genetic Testing-Health Care Issues:An Interview with Dr. Neil Holzman
An excerpt from an interview with Dr. Neil Holzman that took place at the "Winding Your Way through DNA" symposium at the University of California San Francisco in 1992. Dr. Holzman is an M.D. and a health policy expert.
Genetic Conditions/ Rare Conditions: Support Groups & Information
Medical Genetics, University of Kansas Medical Center Professionals, educators, or individuals seeking information on genetic conditions or birth defects may find this list helpful; find additional information through the national and the international organizations listed below; or contact a genetic counselor or clinical geneticist.
OMIM Home Page--Online Mendelian Inheritance in Man
This database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor A. McKusick and his colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information. The database contains textual information, pictures, and reference information.
Mendelian Genetics, an interactive computer program which covers the main concepts of genetics
Genetic Counseling, March of Dimes Birth Defects Foundation
Newborn Screening
The Virtual Hospital™ uses the World-Wide Web (WWW) software technology to store, organize, and distribute multimedia textbooks including the Clinician's Handbook of Preventive Services.
DOE Primer on Molecular Genetics
This primer was prepared by Denise Casey (Human Genome Management Information System - Oak Ridge National Laboratory) for the1991-92 DOE Human Genome Program Report.
Home Page for Genetic Professionals
Information for genetic professionals at the University of Kansas Medical Center is updated regularly for genetic counselors, clinical geneticists, and medical geneticists with links to a variety of clinical, research and educational resources.
Genetics & Public Issues
The National Center for Genome Resources (NCGR) in Santa Fe, New Mexico is assembling educational and informational resources for the public, physicians and other professionals. This information is selected to help the public direct and make informed decisions about genetic information, technology and services. It is also selected to help industry and policymakers guide the application of genetic research and biotechnology. .
Geneticists & Ethicists Mentor Network,
Teachers and students can send questions to professionals in genetics, law, public policy, and ethics.

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